ABSTRACT 

The aim of the study is to determine changes in several trace elements in erythrocytes such as cobalt, chromium,
manganese, molybdenum and phosphorous in a chosen group within the students in Al-Esraa University College and the
outcome of the study showed that a physical training everyday (may) motivate some variables in the concentration of some trace
elements.

The silent killer or ovarian cancer (OC) is one of the major causes of cancer deaths among women in the
modern age. In view of the therapeutic roles of platinum based chemotherapy among the ovarian cancer
patients, objective of this report was to assess the effects of the first round of chemotherapy among women
with ovarian cancer. Here, the levels of the pleural markers for cancer bio markers, before and after the
chemotherapy were tested among ovarian cancer patients. The biochemical indices may be of use in
deciphering the relation between cancer relapse and platinum retrieval. The pleural analyses pre and post
platinum chemotherapy session demonstrated wide range of biochemical and protein marker changes among
ovarian cancer patients. The various cancer antigens were variedly reduced post chemotherapy. Hence, it is
proposed that biochemical markers in pleural liquid may serve as better indicators and early diagnostic tools
for ovarian cancer.

Subject: Polycystic ovary syndrome (PCOS) is female disorder caused by cysts formation in ovarian that results disorder of hormones secretion and menstrual cycle. Neuregulin 4 (NRG4) is one of adipokines family members synthesis and release via adipose tissues, it acts as activator the epidermal growth factor receptor (EGFR).

Objective of the Study: Assessment role of NRG4 in PCOS patients.

Materials and Methods: Present study included 30 PCOS patients with 30 controls, the age individuals of tow group at study were 18 years and above of females. At this study measured serum NRG4 level by quantity method for all study individuals, the body mass index (BMI) also measured for all study individuals.

Results: Present study explain increase of NRG4 level in serum samples and BMI in PCOS patients group compared with control group.

Conclusion: Current study demonstrate role of NRG4 level that act as compensate mechanism in PCOS disorder.